HMM Summary Page: TIGR04278
Accession | TIGR04278 |
Name | viperin |
Function | antiviral radical SAM protein viperin |
Trusted Cutoff | 450.00 |
Domain Trusted Cutoff | 450.00 |
Noise Cutoff | 425.00 |
Domain Noise Cutoff | 425.00 |
Isology Type | equivalog |
HMM Length | 347 |
Author | Haft DH |
Entry Date | Feb 2 2012 3:21PM |
Last Modified | Feb 10 2012 10:37AM |
Comment | Viperin (Virus Inhibitory Protein, ER-associated, Iterferon-inducible) is a radical SAM enzyme found in human and other vertebrates. It is both induced by interferon and demonstrably active in blocking replication by several types of virus, apparently by modifying lipid chemistries in lipid droplets and membrane rafts. |