HMM Summary Page: TIGR04278

Functionantiviral radical SAM protein viperin
Trusted Cutoff450.00
Domain Trusted Cutoff450.00
Noise Cutoff425.00
Domain Noise Cutoff425.00
Isology Typeequivalog
HMM Length347
AuthorHaft DH
Entry DateFeb 2 2012 3:21PM
Last ModifiedFeb 10 2012 10:37AM
CommentViperin (Virus Inhibitory Protein, ER-associated, Iterferon-inducible) is a radical SAM enzyme found in human and other vertebrates. It is both induced by interferon and demonstrably active in blocking replication by several types of virus, apparently by modifying lipid chemistries in lipid droplets and membrane rafts.