HMM Summary Page: TIGR04267
Accession | TIGR04267 |
Name | mod_HExxH |
Function | HEXXH motif domain |
Trusted Cutoff | 25.00 |
Domain Trusted Cutoff | 25.00 |
Noise Cutoff | 24.00 |
Domain Noise Cutoff | 24.00 |
Isology Type | domain |
HMM Length | 399 |
Author | Haft DH |
Entry Date | Jan 22 2012 2:03PM |
Last Modified | Feb 10 2012 10:37AM |
Comment | Some proteins with this domain toward the C-terminus have an N-terminal region with a radical SAM domain (PF04055) and a SPASM domain (TIGR04085), a combination frequently associated with peptide modification. All seed alignment members, and all family members that are not fused to a radical SAM domain, have a motif HEXXH that suggests metalloprotease activity. A role in peptide or protein maturation is suggested. |