HMM Summary Page: TIGR04252

FunctionSynChlorMet cassette protein ScmA
Gene SymbolscmA
Trusted Cutoff35.00
Domain Trusted Cutoff35.00
Noise Cutoff25.00
Domain Noise Cutoff25.00
Isology Typehypoth_equivalog
HMM Length49
AuthorHaft DH
Entry DateDec 22 2011 5:29PM
Last ModifiedFeb 10 2012 10:37AM
CommentA biosynthesis cassette found in Syntrophobacter fumaroxidans MPOB, Chlorobium limicola DSM 245, Methanocella paludicola SANAE, and delta proteobacterium NaphS2 contains two PqqE-like radical SAM/SPASM domain proteins, a PqqD homolog, and a conserved hypothetical protein. This HMM identifies a conserved open reading frame that was identified as a predicted gene in only one of those species (Chlorobium), but that may represent the ribosomally produced peptide precursor of the system. As with most other radical SAM enzyme-modified ribosomal natural products, these polypeptides are Cys-rich in the C-terminal half.
Genome PropertyGenProp1029: radical SAM/SPASM system SynChlorMet (HMM)