HMM Summary Page: TIGR04248

FunctionSynChlorMet cassette protein ScmD
Gene SymbolscmD
Trusted Cutoff100.00
Domain Trusted Cutoff100.00
Noise Cutoff80.00
Domain Noise Cutoff80.00
Isology Typeequivalog
HMM Length84
AuthorHaft DH
Entry DateDec 22 2011 8:46AM
Last ModifiedFeb 10 2012 10:37AM
CommentA biosynthesis cassette found in Syntrophobacter fumaroxidans MPOB, Chlorobium limicola DSM 245, Methanocella paludicola SANAE, and delta proteobacterium NaphS2 contains two PqqE-like radical SAM/SPASM domain proteins, a PqqD homolog, and a conserved hypothetical protein. These components suggest modification of a ribosomally produced peptide precursor, but the precursor has not been identified. Members of this family are the PqqD-like protein.
ReferencesRN [1] RM PMID:20737074 RT Interaction of PqqE and PqqD in the pyrroloquinoline quinone (PQQ) biosynthetic pathway links PqqD to the radical SAM superfamily. RA Wecksler SR, Stoll S, Iavarone AT, Imsand EM, Tran H, Britt RD, Klinman JP RL Chem Commun (Camb). 2010 Oct 7;46(37):7031-3.
Genome PropertyGenProp1029: radical SAM/SPASM system SynChlorMet (HMM)