HMM Summary Page: TIGR04207

Functionsurface glycoprotein signal peptide
Trusted Cutoff24.60
Domain Trusted Cutoff24.60
Noise Cutoff24.00
Domain Noise Cutoff23.50
Isology Typedomain
HMM Length30
AuthorHaft DH
Entry DateSep 26 2011 10:17AM
Last ModifiedFeb 10 2012 10:37AM
CommentThis N-terminal homology domain appears to be a specialized class of signal peptide. It occurs mostly in the halophilic archaea, primarily on proteins with the C-terminal PGF-CTERM domain, including the S-layer-forming major surface glycoprotein of several species. The PGF-CTERM domain is the putative archaeosortase A recognition sequence. However, this N-terminal domain occurs also in several archaeal proteins that lack PGF-CTERM, and occurs in bacteria on a protein from Clostridium leptum DSM 753.