HMM Summary Page: TIGR04185

FunctionATP-grasp ribosomal peptide maturase, MvdC family
Trusted Cutoff425.00
Domain Trusted Cutoff425.00
Noise Cutoff400.00
Domain Noise Cutoff400.00
Isology Typeequivalog
HMM Length318
AuthorHaft DH
Entry DateAug 7 2011 11:40AM
Last ModifiedFeb 10 2012 10:37AM
CommentThe pair of ATP-grasp proteins MvdD and MvdC (microviridin D and C), as well as an acetyltransferase, produce microviridin K, an example of a RiPP (ribosomally synthesized and posttranslationally modified peptide). Microviridins are peptidase inhibitors. This family includes MvdC and corresponding members of similar cassettes.
ReferencesRN [1] RM PMID:19035375 RT Post-translational modification in microviridin biosynthesis. RA Philmus B, Christiansen G, Yoshida WY, Hemscheidt TK RL Chembiochem. 2008 Dec 15;9(18):3066-73.
Genome PropertyGenProp0991: ATP-grasp maturase system, microviridin/marinostatin class (HMM)