HMM Summary Page: TIGR04172

FunctionDNA phosphorothioation-associated DGQHR protein 1
Trusted Cutoff450.00
Domain Trusted Cutoff450.00
Noise Cutoff250.00
Domain Noise Cutoff250.00
Isology Typehypoth_equivalog
HMM Length381
AuthorHaft DH
Entry DateMay 31 2011 1:35PM
Last ModifiedFeb 10 2012 11:48AM
CommentThe DND system produces an phosphorothioation modification to DNA, replacing a non-bridging oxygen of a phosphate group with sulfur. The modification causes DNA degradation during electrophoresis in Tris buffer. This protein, like DndB (TIGR03233), contains a DGQHR domain (TIGR03187), which also occurs in several contexts that suggest lateral transfer rather than DNA phosphorothioation-dependent restriction.
ReferencesRN [1] RM PMID:22070167 RT ProPhylo: partial phylogenetic profiling to guide protein family construction and assignment of biological process. RA Basu MK, Selengut JD, Haft DH RL BMC Bioinformatics. 2011 Nov 9;12:434.