HMM Summary Page: TIGR04171

Functionribonucleoside-diphosphate reductase, class 1b, beta subunit
Gene SymbolnrdF
Trusted Cutoff355.00
Domain Trusted Cutoff355.00
Noise Cutoff270.00
Domain Noise Cutoff270.00
Isology Typeexception
EC Number1.17.4.1
HMM Length316
AuthorHaft DH
Entry DateMay 27 2011 12:32PM
Last ModifiedMay 27 2011 12:43PM
CommentMembers of this family are NrdF, the beta subunit of class 1b ribonucleotide reductase. This form uses a dimanganese moiety associated with a tyrosine radical to reduce the cellular requirement for iron.
ReferencesRN [1] RM PMID:21561096 RT Bacillus subtilis Class Ib Ribonucleotide Reductase is a Dimanganese(III)-Tyrosyl Radical Enzyme. RA Zhang Y, Stubbe J RL Biochemistry. 2011 May 11.