HMM Summary Page: TIGR04148

Functionradical SAM peptide maturase, GG-Bacteroidales family
Trusted Cutoff300.00
Domain Trusted Cutoff300.00
Noise Cutoff240.00
Domain Noise Cutoff240.00
Isology Typeequivalog
HMM Length411
AuthorHaft DH
Entry DateMar 31 2011 9:44AM
Last ModifiedJun 9 2011 10:12AM
CommentMembers of this protein family are radical SAM enzymes (PF04055) with the additional C-terminal region (TIGR04085) that is frequently a marker of peptide modification. Many members of this family are found in the vicinity of one or several ORFs encoding short polypeptides with a Gly-Gly motif (common for bacteriocin leader peptide cleavage), followed by a Cys-rich patch and then poorly conserved sequences.
ReferencesRN [1] RM PMID:21478363 RT Biological systems discovery in silico: radical S-adenosylmethionine protein families and their target peptides for posttranslational modification. RA Haft DH, Basu MK RL J Bacteriol. 2011 Jun;193(11):2745-55.
Genome PropertyGenProp0984: radical SAM maturase system, GG-Bacteroidales group (HMM)