HMM Summary Page: TIGR04079
| Accession | TIGR04079 |
| Name | phero_cyc_pep |
| Function | KxxxW-cyclized secreted peptide |
| Trusted Cutoff | 35.00 |
| Domain Trusted Cutoff | 20.00 |
| Noise Cutoff | 25.00 |
| Domain Noise Cutoff | 18.00 |
| Isology Type | subfamily |
| HMM Length | 23 |
| Author | Haft DH |
| Entry Date | Oct 29 2010 9:39AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Members of this family are short precursor peptides in which the mature form undergoes a cyclization between a Lys and a Trp four residues away. The modification enzyme appears to be an adjacent encoded radical SAM protein. Genomes encoding this system include Streptococcus thermophilus LMD-9 and Lactococcus lactis subsp. cremoris MG1363, among others. |
| References | RN [1] RM PMID:17921293 RT Control of the transcription of a short gene encoding a cyclic peptide in Streptococcus thermophilus: a new quorum-sensing system? RA Ibrahim M, Guillot A, Wessner F, Algaron F, Besset C, Courtin P, Gardan R, Monnet V RL J Bacteriol. 2007 Dec;189(24):8844-54. Epub 2007 Oct 5. |
| Genome Property | GenProp0954: radical SAM-cylized peptide, Pep1357C family (HMM) |