HMM Summary Page: TIGR04074

Function3' terminal RNA ribose 2'-O-methyltransferase Hen1
Trusted Cutoff340.00
Domain Trusted Cutoff340.00
Noise Cutoff200.00
Domain Noise Cutoff200.00
Isology Typeequivalog
EC Number2.1.1.-
HMM Length462
AuthorHaft DH
Entry DateOct 15 2010 5:36PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are bacterial Hen1, a 3' terminal RNA ribose 2'-O-methyltransferase that acts in bacterial RNA repair. All members of the seed alignment belong to a cassette with the RNA repair enzyme polynucleotide kinase-phosphatase (Pnkp). Chemically similar Hen1 in eukaryotes acts instead on small regulatory RNAs.
ReferencesRN [1] RM PMID:20007328 RT Bacterial Hen1 is a 3' terminal RNA ribose 2'-O-methyltransferase component of a bacterial RNA repair cassette. RA Jain R, Shuman S RL RNA. 2010 Feb;16(2):316-23.
Genome PropertyGenProp0948: RNA repair, Hen1/Pnkp system (HMM)