HMM Summary Page: TIGR04055

Functionputative heme d1 biosynthesis radical SAM protein NirJ2
Gene SymbolnirJ2
Trusted Cutoff500.00
Domain Trusted Cutoff500.00
Noise Cutoff425.00
Domain Noise Cutoff425.00
Isology Typeequivalog
EC Number1.3.99.-
HMM Length326
AuthorHaft DH
Entry DateJul 28 2010 10:37AM
Last ModifiedJun 27 2014 1:54PM
CommentMembers of this radical SAM protein subfamily, designated NirJ2, occur in genomic contexts with a paralog NirJ1 and with other nitrite reductase operon genes associated with heme d1 biosynthesis, as in Heliobacillus mobilis and Heliophilum fasciatum. NirJ2 is presumed by bioinformatics analysis (Xiong, et al.) to be a heme d1 biosynthesis protein by context. This model has been redone (2014) to remove the branch (TIGR04545) that included DVU_0855, from a similar pathway for heme b biosynthesis.
ReferencesRN [1] RM PMID:17906152 RT Insight into the haem d1 biosynthesis pathway in heliobacteria through bioinformatics analysis. RA Xiong J, Bauer CE, Pancholy A RL Microbiology. 2007 Oct;153(Pt 10):3548-62.