HMM Summary Page: TIGR04024

Functioncoenzyme F420-dependent oxidoreductase, NP1902A family
Trusted Cutoff345.40
Domain Trusted Cutoff345.40
Noise Cutoff293.45
Domain Noise Cutoff293.45
Isology Typehypoth_equivalog
EC Number1.14.-.-
HMM Length330
AuthorHaft DH
Entry DateJun 18 2010 4:21PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis subfamily of the luciferase-like monooxygenases is restricted to the order Halobacteriales. SIMBAL analysis strongly suggests this oxidoreductase binds coenzyme F420 rather than FMN. Occasional annotations of members of this family as N5,N10-methylenetetrahydromethanopterin reductase appear to represent overly aggressive transfer of annotation.
ReferencesRN [1] RM PMID:20675471 RT Unexpected abundance of coenzyme F(420)-dependent enzymes in Mycobacterium tuberculosis and other actinobacteria. RA Selengut JD, Haft DH RL J Bacteriol. 2010 Nov;192(21):5788-98.
Genome PropertyGenProp0002: coenzyme F420 utilization (HMM)