HMM Summary Page: TIGR04003

Function[benzylsuccinate synthase]-activating enzyme
Gene SymbolbssD
Trusted Cutoff496.45
Domain Trusted Cutoff496.45
Noise Cutoff496.25
Domain Noise Cutoff496.25
Isology Typeequivalog
EC Number1.97.-.-
HMM Length314
AuthorHaft DH
Entry DateMay 25 2010 5:28PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this radical SAM protein family are [benzylsuccinate synthase]-activating enzyme, a glycyl radical active site-creating enzyme related to [pyruvate formate-lyase]-activating enzyme and additional uncharacterized homologs activating additional glycyl radical-containing enzymes.
ReferencesRN [1] RM PMID:8706665 RT Evidence that anaerobic oxidation of toluene in the denitrifying bacterium Thauera aromatica is initiated by formation of benzylsuccinate from toluene and fumarate. RA Biegert T, Fuchs G, Heider J RL Eur J Biochem. 1996 Jun 15;238(3):661-8. RN [2] RM PMID:9632263 RT Biochemical and genetic characterization of benzylsuccinate synthase from Thauera aromatica: a new glycyl radical enzyme catalysing the first step in anaerobic toluene metabolism. RA Leuthner B, Leutwein C, Schulz H, Horth P, Haehnel W, Schiltz E, Schagger H, Heider J RL Mol Microbiol. 1998 May;28(3):615-28.