HMM Summary Page: TIGR04001
| Accession | TIGR04001 |
| Name | thiol_BshB1 |
| Function | bacillithiol biosynthesis deacetylase BshB1 |
| Gene Symbol | bshB1 |
| Trusted Cutoff | 182.50 |
| Domain Trusted Cutoff | 182.50 |
| Noise Cutoff | 151.25 |
| Domain Noise Cutoff | 151.25 |
| Isology Type | equivalog |
| EC Number | 3.-.-.- |
| HMM Length | 226 |
| Author | Haft DH |
| Entry Date | May 21 2010 12:06PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Members of this protein family are BshB1 (YpjG), an enzyme of bacillithiol biosynthesis; either BshB1 or BshB2 (YojG) must be present, and often both are present. Bacillithiol is a low-molecular-weight thiol, an analog of glutathione and mycothiol, and is found largely in the Firmicutes. |
| References | RN [1] RM PMID:20308541 RT Biosynthesis and functions of bacillithiol, a major low-molecular-weight thiol in Bacilli. RA Gaballa A, Newton GL, Antelmann H, Parsonage D, Upton H, Rawat M, Claiborne A, Fahey RC, Helmann JD RL Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6482-6. |
| Genome Property | GenProp0927: bacillithiol biosynthesis (HMM) |