HMM Summary Page: TIGR03998

Functionbacillithiol biosynthesis cysteine-adding enzyme BshC
Gene SymbolbshC
Trusted Cutoff265.80
Domain Trusted Cutoff265.80
Noise Cutoff218.60
Domain Noise Cutoff218.60
Isology Typeequivalog
HMM Length529
AuthorHaft DH
Entry DateMay 20 2010 4:25PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are BshC, an enzyme required for bacillithiol biosynthesis and described as a cysteine-adding enzyme. Bacillithiol is a low-molecular-weight thiol, an analog of glutathione and mycothiol, and is found largely in the Firmicutes.
ReferencesRN [1] RM PMID:20308541 RT Biosynthesis and functions of bacillithiol, a major low-molecular-weight thiol in Bacilli. RA Gaballa A, Newton GL, Antelmann H, Parsonage D, Upton H, Rawat M, Claiborne A, Fahey RC, Helmann JD RL Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6482-6.
Genome PropertyGenProp0927: bacillithiol biosynthesis (HMM)