HMM Summary Page: TIGR03994

Functioncoproporphyrinogen dehydrogenase HemZ
Gene SymbolhemZ
Trusted Cutoff321.40
Domain Trusted Cutoff321.40
Noise Cutoff259.85
Domain Noise Cutoff259.85
Isology Typeequivalog
EC Number1.3.99.22
HMM Length401
AuthorHaft DH
Entry DateMay 6 2010 10:46AM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this radical SAM protein family are HemZ, a protein involved in coproporphyrinogen III decarboxylation. Alternative names for this enzyme (EC include coproporphyrinogen dehydrogenase and oxygen-independent coproporphyrinogen III oxidase. The family is related to, but distinct from HemN, and in Bacillus subtilis was shown to be connected to peroxide stress and catalase formation.
ReferencesRN [1] RM PMID:10498703 RT Transcriptional control of Bacillus subtilis hemN and hemZ. RA Homuth G, Rompf A, Schumann W, Jahn D RL J Bacteriol. 1999 Oct;181(19):5922-9.