HMM Summary Page: TIGR03988

Functionmycothiol system anti-sigma-R factor
Gene SymbolrsrA
Trusted Cutoff62.50
Domain Trusted Cutoff62.50
Noise Cutoff46.30
Domain Noise Cutoff46.30
Isology Typeequivalog
HMM Length77
AuthorHaft DH
Entry DateApr 19 2010 11:52AM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this family are the anti-sigma-R factor RsrA, which contains a CXXC motif as a thiol-disulphide redox switch. It interacts with sigma-R. It regulates and is regulated by the mycothiol system, which occurs in many actinomycetes.
ReferencesRN [1] RM PMID:18430082 RT Mycothiol regulates and is regulated by a thiol-specific antisigma factor RsrA and sigma(R) in Streptomyces coelicolor. RA Park JH, Roe JH RL Mol Microbiol. 2008 May;68(4):861-70.
Genome PropertyGenProp0923: mycothiol system (HMM)