HMM Summary Page: TIGR03976

FunctionHis-Xaa-Ser system protein HxsD
Gene SymbolhxsD
Trusted Cutoff50.00
Domain Trusted Cutoff50.00
Noise Cutoff30.00
Domain Noise Cutoff30.00
Isology Typehypoth_equivalog
HMM Length90
AuthorHaft DH
Entry DateMar 26 2010 4:17PM
Last ModifiedJun 9 2011 9:48AM
CommentThis rare conserved hypothetical protein of small size occurs exclusively, and perhaps universally, in the context of a pair of (uncharacterized) radical SAM proteins, TIGR03977 and TIGR03978. Many members of this family have invariant motifs LYW and LLNDYxLRE, but PSI-BLAST starting from family members well below 20 % pairwise sequence identity to this group eventually brings in the entire family as modeled here. The family TIGR03979 represents the fourth regularly conserved member of this system.
ReferencesRN [1] RM PMID:21478363 RT Biological systems discovery in silico: radical S-adenosylmethionine protein families and their target peptides for posttranslational mo dification. RA Haft DH, Basu MK RL J Bacteriol. 2011 Jun;193(11):2745-55.
Genome PropertyGenProp0921: radical SAM pair and His-Xaa-Ser repeats peptide (HMM)