HMM Summary Page: TIGR03971

FunctionSDR family mycofactocin-dependent oxidoreductase
Trusted Cutoff300.00
Domain Trusted Cutoff300.00
Noise Cutoff295.00
Domain Noise Cutoff295.00
Isology Typesubfamily
EC Number1.1.99.-
HMM Length271
AuthorHaft DH
Entry DateMar 24 2010 12:53PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein subfamily are putative oxidoreductases belonging to the larger SDR family. All members occur in genomes that encode a cassette for the biosynthesis of mycofactocin, a proposed electron carrier of a novel redox pool. Characterized members of this family are described as NDMA-dependent, meaning that a blue aniline dye serving as an artificial electron acceptor is required for members of this family to cycle in vitro, since the bound NAD residue is not exchangeable. See EC
ReferencesRN [1] RM PMID:21223593 RT Bioinformatic evidence for a widely distributed, ribosomally produced electron carrier precursor, its maturation proteins, and its nicotinoprotein redox partners. RA Haft DH RL BMC Genomics. 2011 Jan 11;12(1):21.
Genome PropertyGenProp0917: mycofactocin system (HMM)