Accession | TIGR03966 |
Name | actino_HemFlav |
Function | heme/flavin dehydrogenase, mycofactocin system |
Gene Symbol | mftD |
Trusted Cutoff | 470.85 |
Domain Trusted Cutoff | 470.85 |
Noise Cutoff | 470.65 |
Domain Noise Cutoff | 470.65 |
Isology Type | hypoth_equivalog |
EC Number | 1.-.-.- |
HMM Length | 385 |
Author | Haft DH |
Entry Date | Mar 22 2010 11:20AM |
Last Modified | Feb 20 2011 5:52PM |
Comment | Members of this protein family possess an N-terminal heme-binding domain and C-terminal flavodehydrogenase domain, and share homology to yeast flavocytochrome b2, to E. coli L-lactate dehydrogenase [cytochrome], to (S)-mandelate dehydrogenase, etc. This enzyme appears only in the context of the mycofactocin system. Interestingly, it is absent from the four species detected so far with mycofactocin but without an F420 biosynthesis system. |
References | RN [1]
RM PMID:21223593
RT Bioinformatic evidence for a widely distributed, ribosomally produced electron carrier precursor, its maturation proteins, and its nicotinoprotein redox partners.
RA Haft DH
RL BMC Genomics. 2011 Jan 11;12(1):21. |
Genome Property | GenProp0917: mycofactocin system (HMM) |