HMM Summary Page: TIGR03962
| Accession | TIGR03962 |
| Name | mycofact_rSAM |
| Function | mycofactocin radical SAM maturase |
| Gene Symbol | mftC |
| Trusted Cutoff | 265.00 |
| Domain Trusted Cutoff | 265.00 |
| Noise Cutoff | 225.00 |
| Domain Noise Cutoff | 225.00 |
| Isology Type | equivalog |
| HMM Length | 339 |
| Author | Haft DH |
| Entry Date | Mar 19 2010 4:41PM |
| Last Modified | Jun 20 2012 11:45AM |
| Comment | Members of this family are uncharacterized radical SAM proteins from the Mycobacterium tuberculosis and many other Actinobacteria, as well as some deltaproteobacteria (e.g. Geobacter uraniireducens), firmicutes (Pelotomaculum thermopropionicum and Desulfotomaculum acetoxidans), and Chloroflexi (Thermomicrobium roseum DSM 5159 and Sphaerobacter thermophilus DSM 20745). They resemble several characterized radical SAM enzymes of peptide modification (PqqE, AlbA), and are always found next to the proposed target, TIGR03969, the putative mycofactocin precursor. |
| References | RN [1] RM PMID:21223593 RT Bioinformatic evidence for a widely distributed, ribosomally produced electron carrier precursor, its maturation proteins, and its nicotinoprotein redox partners. RA Haft DH RL BMC Genomics. 2011 Jan 11;12(1):21. |
| Genome Property | GenProp0917: mycofactocin system (HMM) |