| Accession | TIGR03957 |
| Name | rSAM_HmdB |
| Function | 5,10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB |
| Gene Symbol | hmdB |
| Trusted Cutoff | 320.90 |
| Domain Trusted Cutoff | 320.90 |
| Noise Cutoff | 132.70 |
| Domain Noise Cutoff | 132.70 |
| Isology Type | equivalog |
| HMM Length | 317 |
| Author | Haft DH |
| Entry Date | Mar 12 2010 10:02AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Members of this archaeal protein family are HmdB, a partially characterized radical SAM protein with an unusual CX5CX2C motif. Its gene flanks the H2-forming methylene-H4-methanopterin dehydrogenase gene hmdA, found in hydrogenotrophic methanogens. HmdB appears to act in in biosynthesis of the novel cofactor of HmdA. |
| References | RN [1]
RM PMID:19897660
RT Identification and characterization of a novel member of the radical AdoMet enzyme superfamily and implications for the biosynthesis of the Hmd hydrogenase active site cofactor.
RA McGlynn SE, Boyd ES, Shepard EM, Lange RK, Gerlach R, Broderick JB, Peters JW
RL J Bacteriol. 2010 Jan;192(2):595-8. Epub 2009 Nov 6. |
| Genome Property | GenProp0915: hydrogenase, mono-iron type (HMM) |
