HMM Summary Page: TIGR03948

Functionbutyryl-CoA:acetate CoA-transferase
Trusted Cutoff674.80
Domain Trusted Cutoff674.80
Noise Cutoff514.65
Domain Noise Cutoff514.65
Isology Typeequivalog
EC Number2.8.3.-
HMM Length445
AuthorHaft DH
Entry DateMar 3 2010 12:00PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis enzyme represents one of at least two mechanisms for reclaiming CoA from butyryl-CoA at the end of butyrate biosynthesis (an important process performed by some colonic bacteria), namely transfer of CoA to acetate. An alternate mechanism transfers the butyrate onto inorganic phosphate, after which butyrate kinase transfers the phosphate onto ADP, creating ATP.
ReferencesRN [1] RM PMID:19807780 RT Diversity of human colonic butyrate-producing bacteria revealed by analysis of the butyryl-CoA:acetate CoA-transferase gene. RA Louis P, Young P, Holtrop G, Flint HJ RL Environ Microbiol. 2009 Oct 5.
Genome PropertyGenProp0911: butyryl-CoA to butyrate, acetate CoA-transferase pathway (HMM)