| Accession | TIGR03947 |
| Name | viomycin_VioD |
| Function | capreomycidine synthase |
| Gene Symbol | vioD |
| Trusted Cutoff | 390.90 |
| Domain Trusted Cutoff | 390.90 |
| Noise Cutoff | 390.75 |
| Domain Noise Cutoff | 390.75 |
| Isology Type | equivalog |
| HMM Length | 359 |
| Author | Haft DH |
| Entry Date | Feb 25 2010 2:02PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Members of this family are the enzyme capreomycidine synthase, which performs the second of two steps in the biosynthesis of 2S,3R-capreomycidine from arginine. Capreomycidine is an unusual amino acid used by non-ribosomal peptide synthases (NRPS) to make the tuberactinomycin class of peptide antibiotic. The best characterized member is VioD from the biosynthetic pathway for viomycin. |
| References | RN [1]
RM PMID:15368581
RT Formation of the nonproteinogenic amino acid 2S,3R-capreomycidine by VioD from the viomycin biosynthesis pathway.
RA Yin X, McPhail KL, Kim KJ, Zabriskie TM
RL Chembiochem. 2004 Sep 6;5(9):1278-81. |
| Genome Property | GenProp0909: capreomycidine biosynthesis (HMM) |
