| Accession | TIGR03938 |
| Name | deacetyl_PgaB |
| Function | poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB |
| Gene Symbol | pgaB |
| Trusted Cutoff | 321.90 |
| Domain Trusted Cutoff | 321.90 |
| Noise Cutoff | 168.65 |
| Domain Noise Cutoff | 168.65 |
| Isology Type | equivalog |
| EC Number | 3.5.1.- |
| HMM Length | 618 |
| Author | Haft DH |
| Entry Date | Feb 12 2010 2:50PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Two well-characterized systems produce polysaccharide based on N-acetyl-D-glucosamine in straight chains with beta-1,6 linkages. These are encoded by the icaADBC operon in Staphylococcus species, where the system is designated polysaccharide intercellular adhesin (PIA), and the pgaABCD operon in Gram-negative bacteria such as E. coli. Both systems include a putative polysaccharide deacetylase. The PgaB protein, described here, contains an additional domain lacking from its Gram-positive counterpart IcaB (TIGR03933). Deacetylation by this protein appears necessary to allow export through the porin PgaA |
| References | RN [1]
RM PMID:18359807
RT Roles of pgaABCD genes in synthesis, modification, and export of the Escherichia coli biofilm adhesin poly-beta-1,6-N-acetyl-D-glucosamine.
RA Itoh Y, Rice JD, Goller C, Pannuri A, Taylor J, Meisner J, Beveridge TJ, Preston JF 3rd, Romeo T
RL J Bacteriol. 2008 May;190(10):3670-80. Epub 2008 Mar 21. |
| Genome Property | GenProp0907: poly-beta-1,6 N-acetyl-D-glucosamine system, PgaABCD type (HMM) |
