HMM Summary Page: TIGR03935

AccessionTIGR03935
Namefragilysin
Functionfragilysin
Gene Symbolbft
Trusted Cutoff190.70
Domain Trusted Cutoff190.70
Noise Cutoff190.60
Domain Noise Cutoff190.60
Isology Typeequivalog
EC Number3.4.24.74
HMM Length386
AuthorHaft DH
Entry DateFeb 11 2010 7:55PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this family are fragilysin, the Bacteroides fragilis enterotoxin. This enzyme is a Zn metalloprotease. Three distinct subtypes included in this family all are produced by enterotoxigenic (by definition) strains of Bacteroides fragilis.
ReferencesRN [1] RM PMID:10612750 RT A new subtype of the metalloprotease toxin gene and the incidence of the three bft subtypes among Bacteroides fragilis isolates in Japan. RA Kato N, Liu CX, Kato H, Watanabe K, Tanaka Y, Yamamoto T, Suzuki K, Ueno K RL FEMS Microbiol Lett. 2000 Jan 1;182(1):171-6.