HMM Summary Page: TIGR03927

Functiontype VII secretion protein EssA
Gene SymbolessA
Trusted Cutoff32.45
Domain Trusted Cutoff32.45
Noise Cutoff30.00
Domain Noise Cutoff30.00
Isology Typeequivalog
HMM Length151
AuthorHaft DH
Entry DateFeb 3 2010 4:39PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this family are associated with type VII secretion of WXG100 family targets in the Firmicutes, but not in the Actinobacteria. This highly divergent protein family consists largely of a central region of highly polar low-complexity sequence containing occasional LF motifs in weak repeats about 17 residues in length, flanked by hydrophobic N- and C-terminal regions.
ReferencesRN [1] RM PMID:18554323 RT EsaC substrate for the ESAT-6 secretion pathway and its role in persistent infections of Staphylococcus aureus. RA Burts ML, DeDent AC, Missiakas DM RL Mol Microbiol. 2008 Aug;69(3):736-46. Epub 2008 Jun 28.
Genome PropertyGenProp0905: type VII secretion, Firmicutes form (HMM)