HMM Summary Page: TIGR03918

Function[FeFe] hydrogenase H-cluster maturation GTPase HydF
Gene SymbolhydF
Trusted Cutoff325.55
Domain Trusted Cutoff325.55
Noise Cutoff225.00
Domain Noise Cutoff225.00
Isology Typeequivalog
HMM Length392
AuthorHaft DH
Entry DateJan 14 2010 12:56PM
Last ModifiedMay 24 2011 3:00PM
CommentThis model describes the family of the [Fe] hydrogenase maturation protein HypF as characterized in Chlamydomonas reinhardtii and found, in an operon with radical SAM proteins HydE and HydG, in numerous bacteria. It has GTPase activity, can bind an 4Fe-4S cluster, and is essential for hydrogenase activity.
ReferencesRN [1] RM PMID:15082711 RT Discovery of two novel radical S-adenosylmethionine proteins required for the assembly of an active [Fe] hydrogenase. RA Posewitz MC, King PW, Smolinski SL, Zhang L, Seibert M, Ghirardi ML RL J Biol Chem. 2004 Jun 11;279(24):25711-20. Epub 2004 Apr 13.
Genome PropertyGenProp0914: hydrogenase, [FeFe]-dependent (HMM)