HMM Summary Page: TIGR03909

Functionpyrrolysine biosynthesis protein PylC
Gene SymbolpylC
Trusted Cutoff248.30
Domain Trusted Cutoff248.30
Noise Cutoff247.05
Domain Noise Cutoff247.05
Isology Typeequivalog
HMM Length374
AuthorHaft DH
Entry DateJan 5 2010 2:46PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis protein is PylC, part of a three-gene cassette that is sufficient to direct the biosynthesis of pyrrolysine, the twenty-second amino acid, incorporated in some species at a UAG canonical stop codon.
ReferencesRN [1] RM PMID:17204561 RT A natural genetic code expansion cassette enables transmissible biosynthesis and genetic encoding of pyrrolysine. RA Longstaff DG, Larue RC, Faust JE, Mahapatra A, Zhang L, Green-Church KB, Krzycki JA RL Proc Natl Acad Sci U S A. 2007 Jan 16;104(3):1021-6.
Genome PropertyGenProp0312: pyrrolysine (HMM)