| Accession | TIGR03898 |
| Name | lanti_MRSA_kill |
| Function | type 2 lantibiotic, mersacidin/lichenicidin family |
| Trusted Cutoff | 23.50 |
| Domain Trusted Cutoff | 23.50 |
| Noise Cutoff | 22.05 |
| Domain Noise Cutoff | 22.05 |
| Isology Type | subfamily |
| HMM Length | 44 |
| Author | Haft DH |
| Entry Date | Dec 10 2009 9:53AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This HMM recognizes a number of type 2 lantibiotic-type bacteriocins, including mersacidin and lichenicidin. Members often are found as gene pairs encoding two-chain bacteriocins. Maturation is accomplished, at least in part, by a LanM-type enzyme (TIGR03897). This model describes only the leader peptide region. |
| References | RN [1]
RM PMID:19561184
RT Identification of a novel two-peptide lantibiotic, lichenicidin, following rational genome mining for LanM proteins.
RA Begley M, Cotter PD, Hill C, Ross RP
RL Appl Environ Microbiol. 2009 Sep;75(17):5451-60. Epub 2009 Jun 26. |
