HMM Summary Page: TIGR03898

Functiontype 2 lantibiotic, mersacidin/lichenicidin family
Trusted Cutoff23.50
Domain Trusted Cutoff23.50
Noise Cutoff22.05
Domain Noise Cutoff22.05
Isology Typesubfamily
HMM Length44
AuthorHaft DH
Entry DateDec 10 2009 9:53AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM recognizes a number of type 2 lantibiotic-type bacteriocins, including mersacidin and lichenicidin. Members often are found as gene pairs encoding two-chain bacteriocins. Maturation is accomplished, at least in part, by a LanM-type enzyme (TIGR03897). This model describes only the leader peptide region.
ReferencesRN [1] RM PMID:19561184 RT Identification of a novel two-peptide lantibiotic, lichenicidin, following rational genome mining for LanM proteins. RA Begley M, Cotter PD, Hill C, Ross RP RL Appl Environ Microbiol. 2009 Sep;75(17):5451-60. Epub 2009 Jun 26.