HMM Summary Page: TIGR03883

Functionuncharacterized protein, coenzyme F420 biosynthesis associated
Trusted Cutoff171.35
Domain Trusted Cutoff171.35
Noise Cutoff161.10
Domain Noise Cutoff161.10
Isology Typesubfamily
HMM Length346
AuthorSelengut J
Entry DateNov 5 2009 12:29PM
Last ModifiedFeb 14 2011 3:27PM
CommentA phylogenetic tree of the DUF2342 family (TIGR03624) consists of two major branches. One of these branches, modeled here, is observed almost entirely to be found in coenzyme F420 biosynthesizing species of the Actinobacterial, Chloroflexi and Archaeal lineages. The few organisms having genes within this family and lacking F420 biosynthesis may either have an undiscovered F420 transporter, or may represent F420-to-FMN revertants. This family includes a Chloroflexus Aurantiacus protein whose crystal structure has been determined (PDB:3CMN_A). This has been annotated as a putative hydrolase, but the support for that assertion is untraceable. There is no cofactor present in the structure.
Genome PropertyGenProp0002: coenzyme F420 utilization (HMM)