HMM Summary Page: TIGR03871

Functionquinoprotein dehydrogenase-associated probable ABC transporter substrate-binding protein
Trusted Cutoff212.15
Domain Trusted Cutoff212.15
Noise Cutoff194.60
Domain Noise Cutoff194.60
Isology Typesubfamily
HMM Length232
AuthorHaft DH
Entry DateOct 15 2009 5:09PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis protein family, a sister family to TIGR03870, is found more broadly. It occurs a range of PQQ-biosynthesizing species, not just in known methanotrophs. Interpretation of evidence by homology and by direct experimental work suggest two different roles. By homology, this family appears to be the periplasmic substrate-binding protein of an ABC transport family. However, mutational studies and direct characterization for some sequences related to this family suggests this family may act as a maturation chaperone or additional subunit of a methanol dehydrogenase-like enzyme.
ReferencesRN [1] RM PMID:3114231 RT Isolation and nucleotide sequence of the methanol dehydrogenase structural gene from Paracoccus denitrificans. RA Harms N, de Vries GE, Maurer K, Hoogendijk J, Stouthamer AH RL J Bacteriol. 1987 Sep;169(9):3969-75.
Genome PropertyGenProp1101: quinoprotein cytochrome relay system (HMM)