HMM Summary Page: TIGR03868

Functionproposed F420-0 ABC transporter, periplasmic F420-0 binding protein
Trusted Cutoff392.40
Domain Trusted Cutoff392.40
Noise Cutoff392.20
Domain Noise Cutoff392.20
Isology Typehypoth_equivalog
HMM Length287
AuthorSelengut J
Entry DateOct 15 2009 9:38AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis small clade of ABC-type transporter periplasmic binding protein components is found as a three gene cassette along with a permease (TIGR03869) and an ATPase (TIGR03873). The organisms containing this cassette are all Actinobacteria and all contain numerous genes requiring the coenzyme F420. This model was defined based on five such organisms, four of which are lacking all F420 biosynthetic capability save the final side-chain polyglutamate attachment step (via the gene cofE: TIGR01916). In Jonesia denitrificans DSM 20603 and marine actinobacterium PHSC20C1 this cassette is in an apparent operon with the cofE gene and, in PHSC20C1, also with a F420-dependent glucose-6-phosphate dehydrogenase (TIGR03554). Based on these observations we propose that this periplasmic binding protein is a component of an F420-0 (that is, F420 lacking only the polyglutamate tail) transporter.
Genome PropertyGenProp0896: proposed F420-0 transporter (HMM)