HMM Summary Page: TIGR03867

FunctionMprA protease C-terminal rhombosortase-interaction domain
Gene SymbolmprA
Trusted Cutoff19.70
Domain Trusted Cutoff19.70
Noise Cutoff18.35
Domain Noise Cutoff18.35
Isology Typeequivalog_domain
EC Number3.4.21.-
HMM Length27
AuthorHaft DH
Entry DateOct 14 2009 3:29PM
Last ModifiedFeb 10 2012 10:51AM
CommentThis HMM describes the Ralstonia lineage variant of the GlyGly-CTERM domain (TIGR03501), a predicted target for protein sorting and cleavage by rhombosortase, a member of the family of rhomboid proteases. Note that some MprA family proteases are full-length homologs except for the lack of this domain. All members of the present family are predicted serine proteases.
ReferencesRN [1] RM PMID:22194940 RT GlyGly-CTERM and rhombosortase: a C-terminal protein processing signal in a many-to-one pairing with a rhomboid family intramembrane serine protease. RA Haft DH, Varghese N RL PLoS One. 2011;6(12):e28886.
Genome PropertyGenProp0778: protein sorting system, GlyGly-CTERM/rhombosortase (HMM)