HMM Summary Page: TIGR03851

Functioncarbohydrate ABC transporter, N-acetylglucosamine/diacetylchitobiose-binding protein
Gene SymbolngcE
Trusted Cutoff399.65
Domain Trusted Cutoff399.65
Noise Cutoff312.05
Domain Noise Cutoff312.05
Isology Typeequivalog
HMM Length450
Mainrole CategoryTransport and binding proteins
Subrole CategoryCarbohydrates, organic alcohols, and acids
Gene Ontology TermGO:0006032: chitin catabolic process biological_process
GO:0015764: N-acetylglucosamine transport biological_process
GO:0048029: monosaccharide binding molecular_function
GO:0048030: disaccharide binding molecular_function
AuthorHaft DH
Entry DateOct 5 2009 10:34AM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are the substrate-binding protein, a lipid-anchored protein of Gram-positive bacteria in all examples found so far, that include NgcE of the chitin-degrader, Streptomyces olivaceoviridis, and close homologs from other species likely to share the same function. NgcE binds both N-acetylglucosamine and the chitin dimer, N,N'-diacetylchitobiose.
ReferencesRN [1] RM PMID:16428842 RT An enzyme-linked immunosorbent assay (ELISA) to determine the specificity of the sugar-binding protein NgcE, a component of the ABC transporter for N-acetylglucosamine in Streptomyces olivaceoviridis. RA Saito A, Kaku H, Minami E, Fujii T, Ando A, Nagata Y, Schrempf H, Miyashita K RL Biosci Biotechnol Biochem. 2006 Jan;70(1):237-42.