HMM Summary Page: TIGR03834

FunctionEAGR box
Trusted Cutoff34.10
Domain Trusted Cutoff34.10
Noise Cutoff26.10
Domain Noise Cutoff26.10
Isology Typedomain
HMM Length28
Gene Ontology TermGO:0048870: cell motility biological_process
AuthorHaft DH
Entry DateSep 17 2009 10:29AM
Last ModifiedFeb 14 2011 3:27PM
CommentThe EAGR box (Enriched in Aromatic and Glycine Residues) is found in three different proteins of the Mycoplasma genitalium terminal organelle, which acts in both cytadherence and gliding motility. The presence of this domain in a genome predicts the Mycoplasma-type terminal organelle structure, gliding motility, and cytadherence. The EAGR box may occur from one to nine times in a protein.
ReferencesRN [1] RM PMID:17675381 RT Functional analysis of the Mycoplasma genitalium MG312 protein reveals a specific requirement of the MG312 N-terminal domain for gliding motility. RA Burgos R, Pich OQ, Querol E, Pinol J RL J Bacteriol. 2007 Oct;189(19):7014-23.