HMM Summary Page: TIGR03824

Functionflagellar biosynthesis anti-sigma factor FlgM
Gene SymbolflgM
Trusted Cutoff40.75
Domain Trusted Cutoff40.75
Noise Cutoff37.45
Domain Noise Cutoff37.45
Isology Typeequivalog
HMM Length98
AuthorSelengut J
Entry DateSep 10 2009 1:23PM
Last ModifiedFeb 14 2011 3:27PM
CommentFlgM interacts with and inhibits the alternative sigma factor sigma(28) FliA [1,2,3]. The C-terminus of FlgM contains the sigma(28)-binding domain [1].
ReferencesRN [1] RM PMID:19383707 RT Functional characterization of FlgM in the regulation of flagellar synthesis and motility in Yersinia pseudotuberculosis. RA Ding L, Wang Y, Hu Y, Atkinson S, Williams P, Chen S RL Microbiology. 2009 Jun;155(Pt 6):1890-900. Epub 2009 Apr 21. RN [2] RM PMID:19136588 RT Flagellar biogenesis of Xanthomonas campestris requires the alternative sigma factors RpoN2 and FliA and is temporally regulated by FlhA, FlhB, and FlgM. RA Yang TC, Leu YW, Chang-Chien HC, Hu RM RL J Bacteriol. 2009 Apr;191(7):2266-75. Epub 2009 Jan 9. RN [3] RM PMID:17537210 RT Cellular levels and activity of the flagellar sigma factor FliA of Escherichia coli are controlled by FlgM-modulated proteolysis. RA Barembruch C, Hengge R RL Mol Microbiol. 2007 Jul;65(1):76-89. Epub 2007 May 30.
Genome PropertyGenProp0884: flagellar regulation (HMM)