HMM Summary Page: TIGR03811

Functiontyrosine decarboxylase
Gene Symboltdc
Trusted Cutoff905.30
Domain Trusted Cutoff905.30
Noise Cutoff599.00
Domain Noise Cutoff599.00
Isology Typeequivalog
EC Number4.1.1.25
HMM Length608
Mainrole CategoryCellular processes
Subrole CategoryAdaptations to atypical conditions
Gene Ontology TermGO:0004837: tyrosine decarboxylase activity molecular_function
GO:0006572: tyrosine catabolic process biological_process
AuthorHaft DH
Entry DateAug 31 2009 4:26PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis model represents tyrosine decarboxylases in the family of the Enterococcus faecalis enzyme Tdc. These enzymes often are encoded next to tyrosine/tyramine antiporter, together comprising a system in which tyrosine decarboxylation can protect against exposure to acid conditions. This clade differs from the archaeal tyrosine decarboxylases associated with methanofuran biosynthesis.
ReferencesRN [1] RM PMID:12089039 RT Identification of the Enterococcus faecalis tyrosine decarboxylase operon involved in tyramine production. RA Connil N, Le Breton Y, Dousset X, Auffray Y, Rince A, Prevost H RL Appl Environ Microbiol. 2002 Jul;68(7):3537-44.
Genome PropertyGenProp0875: decarboxylation/antiport proton-motive cycle: tyrosine-tyramine (HMM)