| Accession | TIGR03788 |
| Name | marine_srt_targ |
| Function | marine proteobacterial sortase target protein |
| Trusted Cutoff | 551.65 |
| Domain Trusted Cutoff | 551.65 |
| Noise Cutoff | 550.25 |
| Domain Noise Cutoff | 550.25 |
| Isology Type | equivalog |
| HMM Length | 629 |
| Author | Haft DH |
| Entry Date | Jun 23 2009 1:48PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Members of this protein family are restricted to the Proteobacteria. Each contains a C-terminal sortase-recognition motif, transmembrane domain, and basic residues cluster at the the C-terminus, and is encoded adjacent to a sortase gene. This protein is frequently the only sortase target in its genome, which is as unusual its occurrence in Gram-negative rather than Gram-positive genomes. Many bacteria with this system are marine. In addition to the LPXTG signal, members carry a vault protein inter-alpha-trypsin inhibitor domain (PF08487) and a von Willebrand factor type A domain (PF00092). |
| References | RN [1]
RM PMID:15102780
RT A comparative genome analysis identifies distinct sorting pathways in gram-positive bacteria.
RA Comfort D, Clubb RT
RL Infect Immun. 2004 May;72(5):2710-22. |
| Genome Property | GenProp0859: protein sorting system, proteobacterial dedicated sortase type (HMM) |
