| Accession | TIGR03778 |
| Name | VPDSG_CTERM |
| Function | VPDSG-CTERM protein sorting domain |
| Trusted Cutoff | 22.00 |
| Domain Trusted Cutoff | 22.00 |
| Noise Cutoff | 21.00 |
| Domain Noise Cutoff | 21.00 |
| Isology Type | subfamily_domain |
| HMM Length | 24 |
| Author | Haft DH |
| Entry Date | Jun 17 2009 3:18PM |
| Last Modified | Feb 10 2012 12:18PM |
| Comment | Through in silico analysis, we previously described the PEP-CTERM/exosortase system (PMID:16930487). This model describes a PEP-CTERM-like variant C-terminal protein sorting signal, as found at the C-terminus of twenty otherwise unrelated proteins in Verrucomicrobiae bacterium DG1235. The variant motif, VPDSG, seems an intermediate between the VPEP motif (TIGR02595) of typical exosortase systems and the classical LPXTG of sortase in Gram-positive bacteria. |
| References | RN [1]
RM PMID:22037399
RT Archaeosortases and exosortases are widely distributed systems linking membrane transit with posttranslational modification.
RA Haft DH, Payne SH, Selengut JD
RL J Bacteriol. 2012 Jan;194(1):36-48. Epub 2011 Oct 28. |
| Genome Property | GenProp0985: protein sorting system, VPDSG-CTERM/exosortase C (HMM) |
