HMM Summary Page: TIGR03766

Functionconserved hypothetical integral membrane protein
Trusted Cutoff288.45
Domain Trusted Cutoff288.45
Noise Cutoff264.50
Domain Noise Cutoff264.50
Isology Typehypoth_equivalog
HMM Length483
AuthorHaft DH
Entry DateJun 2 2009 3:58PM
Last ModifiedFeb 10 2012 12:40PM
CommentModels TIGR03110, TIGR03111, and TIGR03112 describe a three-gene system found in several Gram-positive bacteria, where TIGR03110 (XrtG) is distantly related to a putative transpeptidase, exosortase (TIGR02602). This HMM describes a small clade that correlates by both gene clustering and phyletic pattern, although imperfectly, to the three gene system. Both this narrow clade, and the larger set of full-length homologous integral membrane proteins, have an especially well-conserved region near the C-terminus with an invariant tyrosine. The function is unknown.
ReferencesRN [1] RM PMID:22037399 RT Archaeosortases and exosortases are widely distributed systems linking membrane transit with posttranslational modification. RA Haft DH, Payne SH, Selengut JD RL J Bacteriol. 2012 Jan;194(1):36-48. Epub 2011 Oct 28.
Genome PropertyGenProp0669: protein sorting system, putative, exosortase G class (HMM)