HMM Summary Page: TIGR03748

Functionintegrating conjugative element protein PilL, PFGI-1 class
Trusted Cutoff64.15
Domain Trusted Cutoff64.15
Noise Cutoff48.45
Domain Noise Cutoff48.45
Isology Typehypoth_equivalog_domain
HMM Length105
Mainrole CategoryMobile and extrachromosomal element functions
Subrole CategoryPlasmid functions
AuthorHaft DH
Entry DateMay 19 2009 11:15AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM describes the conserved N-terminal region of a variable length protein family associated with laterally transfered regions flanked by markers of conjugative plasmid integration and/or transposition. Most members of the family have the lipoprotein signal peptide motif. A member of the family from a pathogenicity island in Salmonella enterica serovar Dublin strain was designated PilL for nomenclature consistency with a neighboring gene for the pilin structural protein PilS. However, the species distribution of this protein family tracks much better with markers of conjugal transfer than with markers of PilS-like pilin structure.
ReferencesRN [1] RM PMID:14580391 RT Salmonella enterica serovar Dublin strains which are Vi antigen-positive use type IVB pili for bacterial self-association and human intestinal cell entry. RA Morris C, Tam CK, Wallis TS, Jones PW, Hackett J RL Microb Pathog. 2003 Dec;35(6):279-84.
Genome PropertyGenProp0855: integrating conjugative element, PFGI-1 class (HMM)