HMM Summary Page: TIGR03740

Functionlantibiotic protection ABC transporter, ATP-binding subunit
Trusted Cutoff309.75
Domain Trusted Cutoff309.75
Noise Cutoff277.90
Domain Noise Cutoff277.90
Isology Typesubfamily
HMM Length223
AuthorHaft DH
Entry DateMay 11 2009 9:35AM
Last ModifiedFeb 14 2011 3:27PM
CommentModel TIGR03731 represents the family of all lantibiotics related to gallidermin, including epidermin, mutatin, and nisin. This protein family describes the ATP-binding subunit of a gallidermin/epidermin class lantibiotic protection transporter. It is largely restricted to gallidermin-family lantibiotic biosynthesis and export cassettes, but also occurs in orphan transporter cassettes in species that lack candidate lantibiotic precursor and synthetase genes.
ReferencesRN [1] RM PMID:9770275 RT Producer self-protection against the lantibiotic epidermin by the ABC transporter EpiFEG of Staphylococcus epidermidis Tu3298. RA Otto M, Peschel A, Gotz F RL FEMS Microbiol Lett. 1998 Sep 15;166(2):203-11.
Genome PropertyGenProp0853: lantibiotic system, gallidermin/epidermin family (HMM)