HMM Summary Page: TIGR03725

FunctiontRNA threonylcarbamoyl adenosine modification protein YeaZ
Gene SymbolyeaZ
Trusted Cutoff69.30
Domain Trusted Cutoff69.30
Noise Cutoff67.75
Domain Noise Cutoff67.75
Isology Typeequivalog
HMM Length212
AuthorHaft DH
Entry DateMar 18 2009 4:42PM
Last ModifiedMay 7 2012 5:55PM
CommentThis family describes a protein family, YeaZ, now associated with the threonylcarbamoyl adenosine (t6A) tRNA modification. Members of this family may occur as fusions with ygjD (previously gcp) or the ribosomal protein N-acetyltransferase rimI, and is frequently encoded next to rimI.
ReferencesRN [1] RM PMID:22378793 RT Biosynthesis of Threonylcarbamoyl Adenosine (t6A), a Universal tRNA Nucleoside. RA Deutsch C, El Yacoubi B, de Crecy-Lagard V, Iwata-Reuyl D RL J Biol Chem. 2012 Apr 20;287(17):13666-73. RN [2] RM PMID:16617437 RT Structural characterization of Salmonella typhimurium YeaZ, an M22 O-sialoglycoprotein endopeptidase homolog. RA Nichols CE, Johnson C, Lockyer M, Charles IG, Lamb HK, Hawkins AR, Stammers DK RL Proteins. 2006 Jul 1;64(1):111-23.
Genome PropertyGenProp1060: tRNA N6-threonylcarbamoyladenosine modification (HMM)