HMM Summary Page: TIGR03719

FunctionATP-binding cassette protein, ChvD family
Trusted Cutoff806.75
Domain Trusted Cutoff806.75
Noise Cutoff591.30
Domain Noise Cutoff591.30
Isology Typesubfamily
HMM Length552
Gene Ontology TermGO:0005524: ATP binding molecular_function
GO:0005575: cellular_component cellular_component
GO:0008150: biological_process biological_process
AuthorHaft DH
Entry DateMar 3 2009 3:28PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
ReferencesRN [1] RM PMID:11344138 RT ChvD, a chromosomally encoded ATP-binding cassette transporter-homologous protein involved in regulation of virulence gene expression in Agrobacterium tumefaciens. RA Liu Z, Jacobs M, Schaff DA, McCullen CA, Binns AN RL J Bacteriol. 2001 Jun;183(11):3310-7.