HMM Summary Page: TIGR03718

Functionintegral membrane protein, TerC family
Trusted Cutoff246.40
Domain Trusted Cutoff246.40
Noise Cutoff149.25
Domain Noise Cutoff149.25
Isology Typesubfamily
HMM Length303
Gene Ontology TermGO:0003674: molecular_function molecular_function
GO:0008150: biological_process biological_process
GO:0016021: integral to membrane cellular_component
AuthorHaft DH
Entry DateMar 2 2009 12:15PM
Last ModifiedFeb 14 2011 3:27PM
CommentRfam model RF00080 describes a structured RNA element called the yybP-ykoY leader, or SraF, which may precede one or several genes in a genome. Members of this highly hydrophobic protein family often are preceded by a yybP-ykoY leader, which may serve as a riboswitch. From the larger group of TerC homologs (PF03741), this subfamily contains TerC itself from Alcaligenes sp. plasmid IncHI2 pMER610 and from Proteus mirabilis. It also contains the alkaline-inducible E. coli protein Alx, which unlike the two TerC examples is preceded by a yybP-ykoY leader.
ReferencesRN [1] RM PMID:3049247 RT The nucleotide sequence of a plasmid determinant for resistance to tellurium anions. RA Jobling MG, Ritchie DA RL Gene. 1988 Jun 30;66(2):245-58. RN [2] RM PMID:12724390 RT An inducible tellurite-resistance operon in Proteus mirabilis. RA Toptchieva A, Sisson G, Bryden LJ, Taylor DE, Hoffman PS RL Microbiology. 2003 May;149(Pt 5):1285-95.