HMM Summary Page: TIGR03716

Functionintegral membrane protein, YkoY family
Trusted Cutoff138.50
Domain Trusted Cutoff138.50
Noise Cutoff123.65
Domain Noise Cutoff123.65
Isology Typesubfamily
HMM Length220
Gene Ontology TermGO:0003674: molecular_function molecular_function
GO:0008150: biological_process biological_process
GO:0016021: integral to membrane cellular_component
AuthorHaft DH
Entry DateMar 2 2009 11:15AM
Last ModifiedFeb 14 2011 3:27PM
CommentRfam model RF00080 describes a structured RNA element called the yybP-ykoY leader, or SraF, which may precede one or several genes in a genome. Members of this highly hydrophobic protein family often are preceded by a yybP-ykoY leader, which may serve as a riboswitch. From the larger group of TerC homologs (PF03741), this subfamily contains proteins YceF and YkoY from Bacillus subtilis. A transport function is proposed.
ReferencesRN [1] RM PMID:15096624 RT New RNA motifs suggest an expanded scope for riboswitches in bacterial genetic control. RA Barrick JE, Corbino KA, Winkler WC, Nahvi A, Mandal M, Collins J, Lee M, Roth A, Sudarsan N, Jona I, Wickiser JK, Breaker RR RL Proc Natl Acad Sci U S A. 2004 Apr 27;101(17):6421-6.