HMM Summary Page: TIGR03711

Functionaccessory Sec system protein Asp3
Gene Symbolasp3
Trusted Cutoff67.25
Domain Trusted Cutoff67.25
Noise Cutoff49.20
Domain Noise Cutoff49.20
Isology Typeequivalog
HMM Length135
Mainrole CategoryProtein fate
Subrole CategoryProtein and peptide secretion and trafficking
Gene Ontology TermGO:0006886: intracellular protein transport biological_process
GO:0008565: protein transporter activity molecular_function
AuthorHaft DH
Entry DateFeb 25 2009 11:39AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis protein is designated Asp3 because, along with SecY2, SecA2, and other proteins it is part of the accessory Sec system. The system is involved in the export of serine-rich glycoproteins important for virulence in a number of Gram-positive species, including Streptococcus gordonii and Staphylococcus aureus. This protein family is assigned to transport rather than glycosylation function, but the specific molecular role is unknown.
ReferencesRN [1] RM PMID:18621893 RT Characterization of the accessory Sec system of Staphylococcus aureus. RA Siboo IR, Chaffin DO, Rubens CE, Sullam PM RL J Bacteriol. 2008 Sep;190(18):6188-96.
Genome PropertyGenProp0844: accessory Sec system for serine-rich glycoprotein transport (HMM)