HMM Summary Page: TIGR03709

Functionpolyphosphate:nucleotide phosphotransferase, PPK2 family
Trusted Cutoff247.20
Domain Trusted Cutoff247.20
Noise Cutoff240.85
Domain Noise Cutoff240.85
Isology Typehypoth_equivalog
EC Number2.7.4.-
HMM Length264
Mainrole CategoryCentral intermediary metabolism
Subrole CategoryPhosphorus compounds
Gene Ontology TermGO:0005575: cellular_component cellular_component
GO:0006797: polyphosphate metabolic process biological_process
GO:0016776: phosphotransferase activity, phosphate group as acceptor molecular_function
AuthorHaft DH
Entry DateJan 23 2009 4:55PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family belong to the polyphosphate kinase 2 (PPK2) family, which is not related in sequence to PPK1. While PPK1 tends to act in the biosynthesis of polyphosphate, or poly(P), members of the PPK2 family tend to use the terminal phosphate of poly(P) to regenerate ATP or GTP from the corresponding nucleoside diphosphate, or ADP from AMP as is the case with polyphosphate:AMP phosphotransferase (PAP). Members of this protein family most likely transfer the terminal phosphate between poly(P) and some nucleotide, but it is not clear which.
Genome PropertyGenProp0840: polyphosphate kinase/exopolyphosphatase system (HMM)